What if this weight regain is caused by bacteria? This was revealed by a scientific study on mice.
With good resolutions coming up in the New Year, and especially the pounds piled on over the holidays, many will be looking to shed excess weight. But the risk of dieting is that we often can’t keep the weight we gain off.
This “yo-yo” effect found in many people, can be scientifically explained.
of Researchers from the Shanghai Institute and the Nutrition Laboratory of the Chinese Academy of Sciences identified the reasons. According to experiments on mice, this often restores weight after the diet.
Why weight gain?
We have known for a long timeafter the diet, the body starts to store fat again, but he does it much easier than before, as if he were stocking up after deprivation. Apart from this logic, scientists could not understand the process and especially the causes.
Chinese researchers started from this postulate to find an answer. They published their results metabolism in natureDecember 1, 2022
10 diets and 3 post-diet diets were studied
After demonstrating that refeeding after various types of diets led to rapid fat accumulation in mice, the researchers also highlighted that increased intestinal absorption of lipids contributed to the increase in fat mass after the diet.
to discover mechanisms remain unknown and what led to that weight regain after a diet, the researchers decided introduce mice to 10 different diets before rnutrition in different ways : a road high proteina low protein and one normal diet in terms of protein dosage.
And the process studied on mice gave very surprising results.
An increase in the number of bacteria
In all three cases, the researchers saw this the number of Lactobacillus bacteria and its metabolites in the intestine increases massively after diet.
“Is associated with increased number of refeedings after short-term dietary restriction Lactobacillus and its metabolites contribute to increased intestinal lipid absorption and postprandial fat mass.”
But they also understood that “high protein diet After short-term dietary restriction, it impairs intestinal lipid absorption and suppresses fat accumulation by inhibiting the growth of Lactobacillus.
To make sure that the weight gain was related to an increase in the presence of bacteria, the scientists then gave antibiotics (penicillin) to some mice to reduce the bacteria, and to others to reduce the bacteria.
Among the fields antibiotic treatment, decreased intestinal absorption of lipids was observed and thus a reduced body fat retention after dieting.
Among the receivers Lactobacilli In addition, aincrease in fat mass.
A high protein diet and taking antibiotics as a solution?
Thus, scientific results will show that a high protein diet A few days after the diet will hold its line. But alsoprevents bacteria whose influence would be responsible for restoring weight for growth in the body.
Or even the combination of the letter Dhigh protein diet with a dose of antibiotics like penicillin.
“We suggest that targeting intestinal Lactobacillus to inhibit intestinal lipid absorption through high-protein diet or antibiotics may be an effective strategy to prevent post-diet obesity,” the Chinese researchers concluded.
It should be tested but be careful, antibiotics are not automatic even for diet. In particular, scientists should demonstrate their conclusions not on mice, but on humans.